Hirayama Noriaki

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Association of HLA-A*11:01 with Sulfonamide-Related Severe Cutaneous Adverse Reactions in Japanese Patients.

Human PZP and common marmoset A2ML1 as pregnancy related proteins.

HLABAP: HLA class I-binding antigenic peptide predictor

Podoplanin is indispensable for cell motility and platelet-induced epithelial-to-mesenchymal transition-related gene expression in esophagus squamous carcinoma TE11A cells.

Preparation and characterization of monoclonal antibodies recognizing two CD4 isotypes of Microminipigs.

A pull-down and slot blot-based screening system for inhibitor compounds of the podoplanin-CLEC-2 interaction.

Effects of interleukin-17A in nucleus pulposus cells and its small-molecule inhibitors for intervertebral disc disease.

Interaction of Nevirapine with the Peptide Binding Groove of HLA-DRB1*01:01 and Its Effect on the Conformation of HLA-Peptide Complex.

TGF-��-induced intracellular PAI-1 is responsible for retaining hematopoietic stem cells in the niche.

A cell-based high-throughput screening assay system for inhibitor compounds of antigen presentation by HLA class II molecule.

In Silico and In Vitro Analysis of Interaction between Ximelagatran and Human Leukocyte Antigen (HLA)-DRB1*07:01.

Docking simulations between drugs and HLA molecules associated with idiosyncratic drug toxicity.

Binding Affinity and Interaction of LL-37 with?HLA-C*06:02 in Psoriasis.

Production of a Locus- and Allele-Specific Monoclonal Antibody for the Characterization of SLA-1*0401 mRNA and Protein Expression Levels in MHC-Defined Microminipigs.

Frequent mutations in NOTCH1 ligand-binding regions in Japanese oral squamous cell carcinoma.

Na+/H+ exchanger 1 is regulated via its lipid-interacting domain, which functions as a molecular switch: a pharmacological approach using indolocarbazole compounds.

A novel acylaminoimidazole derivative, WN1316, alleviates disease progression via suppression of glial inflammation in ALS mouse model.

HLA-Modeler: Automated Homology Modeling of Human Leukocyte Antigens.

A possible molecular mechanism of immunomodulatory activity of bilirubin.

In Silico Prediction of Interactions between Site II on Human Serum Albumin and Profen Drugs.

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The investigation of the new small molecule inhibitors of IL-17A for intervertebral disc disease treatment by In Silico analysis

Analysis of cancer antigens through novel HLA assay

Intervertebral disc regeneration and transcriptional control of nucleus pulpous progenitor cells by in silico pharmacogenesis and iPS technology

The exploration of new drug for the treatment of Notch-active tumor cells.

Development of cultured skin which has tolerance in ischemia.

In silico screening of Interleukin-15 mimetics and application for a treatment of elderly septic patients

The search for HLA inhibitor using short ragweed allergy mouse model.

Integrated redearch for HLA disease and evolution

Genome-wide identification of genes for anorexia and their cascade analysis on disease development by functional study

in silico analysis of molecular interactions between commercially available drugs in Japan and proteins

Development of novel compounds that enhance HIF activity and ameliorate chronic hypoxia in diabetic nephropathy and other diseases.

in silico drug discovery

Structure and function of metal-binding human metallothionein

Construction of cellobiohydrolase from filamentous fungus with endo-type cleavage fashion using protein engineering

Development of stable cholesterol oxidase used for diagnosis

Studies on Molecular Recognition Patterns between Sugars and Amino Acids by Use of the Data Obtained from Single Crystal X-Ray Analysis