亀谷 美恵

Kametani Yoshie

  • 准教授
  • 学位:博士(理学)

基本情報

所属

  • Undergraduate School of Medicine / Faculty of Medicine
  • Micro/Nano Technology Center

詳細情報

研究キーワード

  • peptide vaccine
  • pregnant immunity
  • humanized mouse

研究分野

  • Life sciences Immunology

論文

Genetic Links between Reproductive Traits and Amino Acid Pairwise Distances of Swine Leukocyte Antigen Alleles among Mating Partners in Microminipigs

Liposome-encapsulated progesterone efficiently suppresses B-lineage cell proliferation

Coccomyxa subellipsoidea KJ Components Enhance the Expression of Metallothioneins and Th17 Cytokines during Human T Cell Activation

PBMC-engrafted humanized mice models for evaluating immune-related and anticancer drug delivery systems.

Antigen/Adjuvant-Displaying Enveloped Viral Replica as a Self-Adjuvanting Anti-Breast-Cancer Vaccine Candidate

Construction of the systemic anticancer immune environment in tumour-bearing humanized mouse by using liposome-encapsulated anti-programmed death ligand 1 antibody-conjugated progesterone.

Genetic Association between Farrowing Rates and Swine Leukocyte Antigen Alleles or Haplotypes in Microminipigs.

Precise immunological evaluation rationalizes the design of a self-adjuvanting vaccine composed of glycan antigen, TLR1/2 ligand, and T-helper cell epitope

Coccomyxa sp.KJ extract affects the fate of T cells stimulated by toxic shock syndrome toxin-1, a superantigen secreted by Staphylococcus aureus.

High-progesterone environment preserves T cell competency by evading glucocorticoid effects on immune regulation.

Tropomyosin-related kinase B (TrkB) full-length isoform is related to advanced-stage clear cell ovarian cancer (CCOC)

Stillbirth rates and their association with swine leucocyte antigen class II haplotypes in Microminipigs.

HER2-antigen-specific humoral immune response in breast cancer lymphocytes transplanted in hu-PBL hIL-4 NOG mice.

Gene structure, expression and polymorphism of the HLA-G locus

Preparation and characterization of monoclonal antibodies recognizing two CD4 isotypes of Microminipigs

A case of insulinoma effectively treated with low-dose diazoxide

Immunological Evaluation of Co-assembling a Lipidated Peptide Antigen and Lipophilic Adjuvants as Self-adjuvanting Anti-breast Cancer Vaccine Candidates.

Analysis of swine MHC class I protein expression by a newly prepared monoclonal antibody

講演?口頭発表等

  • Production of specific IgG against HER2 peptide is decreased in NOG-IL-4-Tg mice transplanted with breast cancer patients PBMC.
  • Comparative study of fully synthetic self-adjuvating cancer vaccine candidates containing tandem repeats of B Cell epitope from HER2
  • Synthesis and Immunological Evaluation of Self-Adjuvanting N-modified Clustered Sialyl-Tn Conjugate Vaccine Candidate.
  • Production of specific IgG against HER2 peptide CH401MAP in NOG-IL-4-Tg mice.

共同研究?競争的資金等の研究課題

Determination of T-B cell epitope for the development of novel anti-flavivirus therapeutic antibodies and contribution to a better understanding of pathogenesis

Fetal signal-mediated maintenance of intrauterine environment

Analysis of the signals induced by the variant isoforms of TrkB expressed on ovarian clear cell adenocarcinoma

Establishment of a humoral immunity evaluation system based on the pregnant immunity system

Functional analysis of HLA ortholog expressed on marmoset placenta

Elucidation of comprehensive MHC information in common marmoset for biomedical studies

Development of experimentation systems related to personalized medicine using humanized NOG mice

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