Akihide Kamiya

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Hepatitis B Virus-KMT2B Integration Drives Hepatic Oncogenic Processes in a Human Gene-edited Induced Pluripotent Stem Cells-derived Model.

Direct neuronal conversion of microglia/macrophages reinstates neurological function after stroke.

Drug metabolic activity as a selection factor for pluripotent stem cell-derived hepatic progenitor cells.

Drug metabolic activity is a critical cell-intrinsic determinant for selection of hepatocytes during long-term culture

Liver Injury and Cell Survival in Non-Alcoholic Steatohepatitis Regulated by Sex-Based Difference through B Cell Lymphoma 6.

Branched-chain amino acids govern the high learning ability phenotype in Tokai high avoider (THA) rats.

Kruppel-like factor 15 induces the development of mature hepatocyte-like cells from hepatoblasts.

Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver.

Ammonia-based enrichment and long-term propagation of zone I hepatocyte-like cells.

Bile duct reconstruction using scaffold-free tubular constructs created by Bio-3D printer.

Liver-specific knockout of B cell lymphoma 6 suppresses progression of non-alcoholic steatohepatitis in mice.

Visualization and isolation of zone-specific murine hepatocytes that maintain distinct cytochrome P450 oxidase expression in primary culture.

Vasoactive Intestinal Peptide Derived from Liver Mesenchymal Cells Mediates Tight Junction Assembly in Mouse Intrahepatic Bile Ducts

A Deactivation Factor of Fibrogenic Hepatic Stellate Cells Induces Regression of Liver Fibrosis in Mice.

Loss of Fibrocystin Promotes Interleukin-8-Dependent Proliferation and CTGF Production of Biliary Epithelium.[Epub ahead of print]

LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells.

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Preparation of a model animal for progressive familial intrahepatic cholestasis using mice with human bile acids

Construction of high-throughput drug discovery screening system using bile duct organoids and fluid devices

Development of treatment for liver diseases using sex difference of liver functions

Fatty acid metabolic system that controls thepathophysiology of steatohepatitis

Exosome Therapy for Liver Cirrhosis Using a Novel Regeneration Factor

Notch Signaling regulates the development of hepatocelular carcinoma.

Establishment of human pluripotent stem cell-derived bile ductal disease analysis system using microfluidic device

Analyses of molecular mechanisms underlying differentiation and proliferation of hepatic stem/progenitor cells for development of novel cell transplantation models

Elucidation of hepatitis virus infection / replication mechanism using genome-modified human pluripotent stem cells

Development of an On-chip Simulator of Hepatic Lobule

Pathophysiological Interplay between Liver Fibrosis, Regeneration and Hepatocarcinogenesis from the Viewpoint of Stem/progenitor Cell Differentiation

Analyses of intrinsic and extrinsic miRNA regulating proliferation of human iPS cell-derived hepatoblats.

Studies on molecular mechanisms regulating fate decision of hepatic stem cells and efficacy of hepatic stem cell transplantation

Establishment of human liver chimeric mice with normal immune system for hepatitis viral infection

Analyses of cell-cell interaction regulating proliferation and differentiation of hepatic stem cells during early-liver development

Research on molecular mechanism of hepatic stem cell proliferation and development of mouse models for stem cell transplantation

Mechanism regulating proliferation and differentiation of liver stem cells