Watanabe Takaaki

基本情報

The fragility of a structurally diverse duplication block triggers recurrent genomic amplification

Mechanisms Underlying Recurrent Genomic Amplification in Human Cancers.

Complex repeat structure promotes hyper-amplification and amplicon evolution through rolling-circle replication.

Impediment of Replication Forks by Long Non-coding RNA Provokes Chromosomal Rearrangements by Error-Prone Restart

Palindromic amplification of the ERBB2 oncogene in primary HER2-positive breast tumors

FOXC1 is involved in ERα silencing by counteracting GATA3 binding and is implicated in endocrine resistance.

Replication fork integrity and intra-S phase checkpoint suppress gene amplification

Homology-mediated end-capping as a primary step of sister chromatid fusion in the breakage-fusion-bridge cycles

Replication-associated DNA double-strand breaks and checkpoint abrogation promote gene amplification.

Double rolling-circle replication (DRCR): Involvement in gene amplification and genome replication including HSV.

Model systems facilitating an understanding of mechanisms for oncogene amplification.

Close Up実験法(Series 227) in vivo高速遺伝子増幅法高品質タンパク質生産の有望なツール

Gene amplification system based on double rolling-circle replication as a model for oncogene-type amplification

Double rolling circle replication (DRCR) is recombinogenic

A novel gene amplification system in yeast based on double rolling-circle replication

癌細胞のゲノム可塑性に関わるDNA複製阻害と長鎖ノンコーディングRNA転写
ダブルローリングサークル複製を中心とする包括的な遺伝子増幅モデル
環状染色体(原核生物)から線状染色体(真核生物)への変化
ダブルローリングサークル複製(DRCR)を起こすゲノムは他にあるか?(Are there any genomes that duplicate through double rolling circle replication (DRCR)?)
ダブルローリングサークル複製を中心とする包括的な遺伝子増幅モデル(A comprehensive model of gene amplification centering on double rolling-circle replication (DRCR))
出芽酵母を用いたダブルローリングサークル型遺伝子増幅依存的な高頻度組換えの検出
ダブルローリングサークル複製を中心とする包括的な遺伝子増幅モデル
ダブルローリングサークル複製(DRCR)を起こすゲノムは他にあるか?
2ミクロンプラスミドを用いたダブルローリングサークル型遺伝子増幅依存的な逆位反応の検出
誘導可能な新規遺伝子増幅系の開発
誘導可能な新規遺伝子増幅系の開発
Gene amplification can be induced under the excessive silencing by the over expression of Sir2p and Sir3p in Saccharomyces cerevisiae
Cre‐lox系を利用した出芽酵母による新規遺伝子増幅系の開発