アブドゥル アジズ ビン イブラヒム

Ibrahim Abd Aziz

  • 講師
  • 学位:博士(医学)

基本情報

所属

  • Undergraduate School of Medicine / Faculty of Medicine

詳細情報

論文

Plasminogen activator inhibitor-1 promotes immune evasion in tumors by facilitating the expression of programmed cell death-ligand 1

Mitochondrial Electron Transport Chain Complex II Dysfunction Causes Premature Aging of Hematopoietic Stem Cells

Plasminogen activator inhibitor type-1 is a negative regulator of hematopoietic regeneration in the adipocyte-rich bone marrow microenvironment

IMiDs uniquely synergize with TKIs to upregulate apoptosis of Philadelphia chromosome-positive acute lymphoblastic leukemia cells expressing a dominant-negative IKZF1 isoform

Inhibition of plasminogen activator inhibitor-1 attenuates against intestinal fibrosis in mice

Targeting of plasminogen activator inhibitor-1 activity promotes elimination of chronic myeloid leukemia stem cells

Blockade of plasminogen activator inhibitor-1 empties bone marrow niche sufficient for donor hematopoietic stem cell engraftment without myeloablative conditioning

TGF-β–induced intracellular PAI-1 is responsible for retaining hematopoietic stem cells in the niche

Inhibition of Plasminogen Activator Inhibitor Type-1 Activity Enhances Rapid and Sustainable Hematopoietic Regeneration

Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells

共同研究?競争的資金等の研究課題

Elucidation of stem cell motility mechanism and its application to regeneration and cancer therapy

To Elucidate the Regulation Mechanism of Hematopoietic Stem Cell's Mobility

Blockade of PAI-1 eliminates leukemic stem cells

Establishment of new method for leukemia therapy by targeting fibrinolytic pathway

Establishment of hematopoietic regeneration by the novel molecular targeting drug

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